PURPOSE: The E/A and E/E` ratio has been used as an indirect factor to evaluate left ventricular diastolic function during echocardiography. In this study, we evaluated the feasibility of E/A and E/E` ratio measured during ECG-gated MDCT.
MATERIALS AND METHODS: Nienty-seven patients examined by both ECG-gated MDCT and echocardiography within one-month interval were recruited as subjects. From the ECG-gated MDCT data with retrospective ECG-gating, left ventricular volume change was measured during one cardiac cycle. The area of mitral valvular orifice was measured in en face view at each cardiac cycle. Trans-mitral-valvular velocities were calculated by dividing LV volume changes with MV orifice areas at 10-phase images for whole cardiac cycle. The ratio between velocities at early-diastolic (E) and late atrial contraction (A) phases was calculated as E/A ratio. Early diastolic mitral annular velocities (E` velocities) were calculated from moved longitudinal distances of mitral valvular annulus during E phase. Moved longitudinal distances of mitral valvular annulus were measured by multiplying changed slice number by slice thickness in en face view. The ratio between trans-mitral-valvular velocities at E phase and E` velocities was calculated as E/E` ratio. The E/A ratio and E/E` ratio were validated based on echocardiographic results.
RESULTS: The E/A ratios and E/E` ratios measured by ECG-gated MDCT and echocardiography showed significant correlation, respectively {R = 0.68 ( p < 0.0001), R=0.77 (p<0.0001), respectively}
CONCLUSIONS: The E/A ratio and E/E` ratio measured by ECG-gated MDCT revealed a significant correlation with echocardiographic results. The E/A ratio and E/E’ ratio could be used as an index for left ventricular diastolic function during ECG-gated MDCT
ⓒ Korean Society of Radiology. All Rights Reserved.
SS 12 CV-08.pdf
