Notification of abstract acceptance
announced via E-mail on July 31st.
Abstract view



Oct. 18 (Thu)  Grand Ballroom 104 Room - SS10 CH
17:30-17:40 [SS 10 CH-10] 
The Feasibility of Three-dimensional CT Densitometry to Evaluate Early Pulmonary Functional Recovery after Bilateral Lung Transplantation: Comparison with The Pulmonary Function Test.
   
● Speaker Sung Ho Hwang (Severance Hospital)
● Authors Sung Ho Hwang,Tea Hoon Kim2,Chul Hwan Park2,Sang Jin Kim2,Hyo Chae Paik2,Min Kwang Byun2
● Affiliation Severance Hospital1,Gangnam Severance Hospital2
● PDF View  SS 10 CH-10.pdf

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PURPOSE:
To evaluate the feasibility of 3-dimensional (3D) computed tomography (CT) densitometry in the assessment of the early pulmonary performance of transplanted lungs.

MATERIALS AND METHODS:
We enrolled 18 patients who underwent sequentially thoracic CT scan and pulmonary function test (PFT) at 1, 3, and 6 months after bilateral lung transplantation, in absence of acute rejection or infection. The transplanted lungs were reconstructed as a 3D model on a commercial workstation, with a threshold of −500 HU. By analysis of histograms, the proportions of lung volumes with attenuation values below −950 and −900 HU were measured. These values were compared with data from PFT.

RESULTS:
Correlation was reasonable between 3D CT densitometric quantitations except the emphysema (<-950 HU) and, the forced expiratory volume in 1 second (FEV1) (r = 0.65, p < 0.05) and the ratio of FEV1 to forced vital capacity (FVC) (r = 0.61, p < 0.05). After operation, mean FEV1 of transplanted lungs at 6 months was improved by 42% over the baseline value at 1 month. 10 patients who achieved above the average of pulmonary function recovery at 6 months tended to show greater than 1,900cc in the lung volume reconstructed with a threshold of -500 HU, regardless of the proportions of the reconstructed lung volume on 3D CT densitometry obtained at 1 month after transplantation.

CONCLUSION:
Lung densitometry with 3D reconstruction of helical CT data can be useful to assess and predict the early functional recovery of transplanted lungs.

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