Notification of abstract acceptance
announced via E-mail on July 31st.
Abstract view



Oct. 18 (Thu)  Grand Ballroom 105 Room - SS05 NR
09:40-09:50 [SS 05 NR-01] 
Acute stroke patients: Direct thrombus visualization at Three-Dimensional Proton Density-Weighted MR Imaging
   
Speaker Jae Sung Yun (Chonbuk National University Hospital)
Authors Jae Sung Yun,Hyo Sung Kwak,Gyoung Ho Chung,Seung Bae Hwang
Affiliation Chonbuk National University Hospital
PDF View  SS 05 NR-01.pdf

PDF File View :
PURPOSE:
To evaluate the accuracy of three-dimensional (3D) proton density (PD)-weighted magnetic resonance (MR) sequences in detection of intra-arterial thrombus in patients with acute symptomatic stroke.

MATERIALS AND METHODS:
Twenty patients with stroke involving the anterior circulation territory underwent MR imaging within 6 hours after initial clinical onset. MR examination include echo-planer T2*-weighted, 3D PD-weightedwith flow suppression, diffusion-weighted (DW), perfusion-weighted (PW), and time-of-flight (TOF) MR angiography. MR angiography and/or cerebral angiography were used as the reference standard to establish the diagnosis on occlusion of intracranial artery. Two neuroradiologists were requested to interpret in a blind study eachecho-planar T2*-weighted MR imaging and 3D PD-weighted MR imaging.The diagnostic accuracy of both sequences was evaluated using the receiver operating characteristic (ROC) analysis. Both sequences were also analyzed for image quality.

RESULTS:
A totalof 19 thrombus in20 patients were includedin this study. The mean area under curve value (Az) of the 3D PD-weighted MR imaging (mean, Az = 0.954) was significantly higher than the echo-planer T2*-weighted MR imaging (mean, Az = 0.671)(p < 0.0001). The mean sensitivity of the 3D PD-weighted MR imaging was significantly higher than the echo-planer T2*-weighted MR imaging (mean, 92.11 versus 36.85, p < 0.0001). The image quality score of the 3D PD-weighted MR imaging was significantly higher than that the echo-planer T2*-weighted MR imaging (mean, 2.90 ¡¾ 0.30 versus 2.18 ¡¾ 0.38, p <0.0001).

CONCLUSION:
Direct visualization of thrombus using 3D PD-weighted MR imaging with flow suppression provides accurate detection of thrombus in patients with suspected acute stroke.

CLINICAL APPLICATION:
The information regarding the detection ofintra-arterial thrombus using 3D PD-weighted MR imaging may be useful in planning various treatment options and may help in assessing the extent of infarct and prognosis.

¨Ï Korean Society of Radiology. All Rights Reserved.