Notification of abstract acceptance
announced via E-mail on July 31st.
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Oct. 18 (Thu)  Grand Ballroom 101 Room - SS01 TH
09:50-10:00 [SS 01 TH-02] 
Does Heterogeneous Echogenicity of the Thyroid Parenchyma Influence the Detection of Multifocality and Bilaterality for Papillary Thyroid Carcinoma on Preoperative Ultrasound Staging?
Speaker Sun Jin Herh (Seoul Veterans Hospital)
Authors Sun Jin Herh,Eun-Kyung Kim2,Jung Hyun Yoon3,Ji Soo Choi4,Hee Jung Suh4,Hee Jung Moon2,Jin Young Kwak2
Affiliation Seoul Veterans Hospital1,Severance Hospital2,Pochon CHA University Bundang Hospital3,National Cancer Center4
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To evaluate whether if heterogeneous echogenicity of the thyroid parenchyma can influence the diagnostic performances of ultrasonography (US) in detection of multifocality and bilaterality of papillary thyroid carcinoma (PTC).

Between December 2010 and January 2011, 162 patients had preoperative staging US for PTC, and underwent total or near-total thyroidectomy. Seven experienced radiologists performed preoperative US for T and N staging. Underlying parenchymal echogenicity of the thyroid gland, multifocality, and bilaterality of the thyroid nodules were also evaluated. Patients were divided into two groups according to the underlying echogenicity of thyroid parenchyma on US. To evaluate the diagnostic accuracy of preoperative staging US according to the underlying thyroid echogenicity, diagnostic performances including sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy were calculated and compared among the two groups.

Of the 162 patients, underlying echogenicity of thyroid was heterogeneous in 42 patients (25.9%), and homogenous in 120 patients (74.1%). Thirty-eight (23.5%) of the 162 patients had multifocal lesions, and 49 (30.2%, 49 of 162) had bilateral lesions on pathologic examination. The incidence of coexistence of PTC with DTD was 37.7%. Diagnostic performances of preoperative staging US did not show significant differences in detecting multifocality and bilaterality between patients with homogenous and heterogeneous parenchymal echogenicity.

Heterogeneous echogenicity of underlying thyroid parenchyma does not significantly influence the detection of multifocality and bilateralityfor PTC on preoperative US staging.

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